Recreational drug Gamma-Butyrolactone




1 recreational drug

1.1 dangers
1.2 addictiveness , dependence
1.3 dose





recreational drug

gbl prodrug of ghb , recreational use comes entirely result of this. bypass ghb restriction laws, home synthesis kits introduced transform gbl and/or 1,4-b ghb.



jugs of seized gbl.



fda warning against products containing ghb , prodrugs, such gbl.


gbl overdose can cause irrational behaviour, severe sickness, coma , death. gbl has distinctive taste , odour, described being comparable stale water, synthetic melon aroma or burnt plastic. differs ghb, described having decidedly salty taste.


dangers

if taken undiluted mouth, gbl can cause esophageal , gastro-intestinal irritation. possible oral ingestion of gbl cause nausea , other similar problems, possibly more ghb.


ghb has biphasic effects, euphoric effect @ low doses (the reason term liquid ecstasy), , sedative effect @ higher doses. result of sedation can cause unconsciousness. when combined alcohol increased sedation , risk of vomiting results in high risk of fatality. many harm reduction organisations suggest never mixing 2 drugs result.


there have been news reports of several deaths associated gbl, in combination alcohol or other depressants.


addictiveness , dependence

frequent use of ghb/gbl, when taken long-term , in moderate doses, not appear cause significant physical dependency in majority of users. in many people, quitting or temporarily abstaining use of drugs achieved minimal or no difficulty. however, when consumed in excessive amounts high frequency of dosing, physical , psychological dependence can develop. management of gbl dependence involves considering person s age, comorbidity , pharmacological pathways of gbl.


there reports of ghb/gbl users adopting 24/7 dosing regime. user has become tolerant effects of drug, increasing dosage , frequency of dosage avoid withdrawal symptoms.


for users report withdrawal symptoms upon quitting use of ghb/gbl, symptoms seem depend on dosage , length of time drug used. light moderate users experience insomnia , sleep-related problems, whereas heavy, prolonged use can cause severe withdrawal symptoms similar benzodiazepine withdrawal syndrome (bws).


dose

a milliliter of pure gbl metabolizes equivalent 1.65g of naghb, common form, doses measured in single milliliter range, either taken @ once or sipped on course of night.








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