Mechanism Protein isoform

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different mechanisms of rna splicing.


alternative splicing post-transcriptional modification process major molecular mechanism contributes protein diversity.


it found spliceosome, large ribonucleoprotein, place rna cleavage , ligation proceeds removal of non protein coding segments or introns. requires 5 subunits, u1,u2, u4/u6 , u5, form active spliceosome.


there 3 main components of common alternative splicing mechanism:



cis-acting regulatory sequences
rna-binding protein splicing factors
rna-rna base pairing

in short, during transcription process, mrna may include (enhance) or exclude (silent) 1 or multiple exons of gene.








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